Merck 106176 Methanol BioRenewable Hypergrade for LC-MS LiChrosolv 2.5 L
Merck 106176 Methanol BioRenewable Hypergrade for LC-MS LiChrosolv 2.5 L
Methanol BioRenewable, hypergrade for LC-MS, LiChrosolv® is a high-purity bio-based solvent designed for liquid chromatography–mass spectrometry applications. Derived from renewable feedstocks, it combines the chromatographic performance requirements of the LiChrosolv® Hypergrade product line with a renewable feedstock approach.
The solvent is suitable for HPLC, LC-MS and LC-MS/MS workflows. Low ionic background and controlled impurities support reproducible mass spectrometric analysis using electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI).

Product Highlights
- BioRenewable methanol derived from renewable feedstocks
- LiChrosolv® Hypergrade for LC-MS
- Assay ≥99.9% (GC)
- Water content ≤0.01%
- Suitable for HPLC and LC-MS applications
- Low ionic background and controlled ion suppression
- Suitable for ESI/APCI ionization methods
- Filtered through a 0.2 µm filter
Technical Specifications
| Brand | Merck |
| Product Line | LiChrosolv® BioRenewable |
| Product Number | 1.06176 |
| Packaging SKU | 1061762500 |
| CAS Number | 67-56-1 |
| Linear Formula | CH3OH |
| Molecular Weight | 32.04 g/mol |
| Grade | Hypergrade for LC-MS |
| Assay | ≥99.9% (GC) |
| Water | ≤0.01% |
| Acidity | ≤0.0002 meq/g |
| Alkalinity | ≤0.0002 meq/g |
| Evaporation Residue | ≤1.0 mg/L |
| UV Transmittance at 210 nm | ≥35% |
| UV Transmittance at 220 nm | ≥60% |
| UV Transmittance at 230 nm | ≥75% |
| UV Transmittance at 260 nm | ≥98% |
| Gradient Grade at 220 nm | ≤2.0 mAU |
| Gradient Grade at 235 nm | ≤1.0 mAU |
| Density | 0.791 g/mL at 25 °C |
| Boiling Point | 64.7 °C |
| Flash Point | 9.7 °C |
| Packaging | 2.5 L |
Applications
- LC-MS and LC-MS/MS mobile phase preparation
- Reversed-phase HPLC
- Gradient elution chromatography
- Pharmaceutical quality control
- Food and beverage analysis
- Natural product analysis
- Analytical method development
BioRenewable Solvent Technology
The LiChrosolv® BioRenewable solvent portfolio uses renewable feedstocks verified through bio-carbon content certification. The solvent is designed to deliver chromatographic resolution, reproducibility and baseline stability comparable to conventional high-purity methanol.
Merck identifies BioRenewable methanol as a drop-in alternative for appropriate established methods. Laboratory-specific quality assurance and validation requirements should still be considered.
Packaging Information
| Packaging Size | 2.5 L |
| Ordering Number | 1061762500 |
| Alternative Packaging | 4 L (1061764000) |
Related Products
Merck 106188: Methanol BioRenewable, gradient grade for liquid chromatography, LiChrosolv®.
Merck 106035: Methanol, Hypergrade for LC-MS, LiChrosolv®.
HPLC Solvents – Product Category
Frequently Asked Questions
Is this methanol suitable for LC-MS? Yes. It is specified by Merck as suitable for LC-MS applications.
What is the difference between Merck 106176 and 106188? Product 106176 is intended for LC-MS applications, while product 106188 is gradient grade for liquid chromatography.
Technical Documentation
Manufacturer Product Information – Merck 106176
Certificate of Analysis (CoA) and Safety Data Sheet (SDS) are available from Merck. Lot-specific certificates may require the batch number.
For product information, availability and quotation requests, please contact info@labor.com.tr.