Sigma-Aldrich 317240 Metformin ≥97% (titration), solid, AMPK signaling activator, Calbiochem® CAS No.: 1115-70-4 5 gr
Category
Brand
Stock Code
LB.SA.317240-5GM
Kısa Bilgi
Synonym(s): Metformin, 1,1-Dimethylbiguanide, Hydrochloride, AMPK Signaling Activator VII Empirical Formula (Hill Notation): C4H11N5 · xHCl CAS Number: 1115-70-4 Molecular Weight: 129.16 (free base basis) MDL number: MFCD00012582 UNSPSC Code: 12352200 NACRES: NA.77
| Sigma-Aldrich 317240 Metformin ≥97% (titration), solid, AMPK signaling activator, Calbiochem® |
| Synonym(s): Metformin, 1,1-Dimethylbiguanide, Hydrochloride, AMPK Signaling Activator VII Empirical Formula (Hill Notation): C4H11N5 · xHCl CAS Number: 1115-70-4 Molecular Weight: 129.16 (free base basis) MDL number: MFCD00012582 UNSPSC Code: 12352200 NACRES: NA.77 |
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PROPERTIES
Product Name Metformin, An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.
Quality Level 100 description Merck USA index - 14, 5938 Assay ≥97% (titration) form solid manufacturer/tradename Calbiochem® storage condition OK to freeze desiccated (hygroscopic) color white solubility water: 50 mg/mL shipped in ambient storage temp. 10-30°C SMILES string Cl.N(C)(C)C(=N\C(=N\[H])\N)N InChI 1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H InChI key OETHQSJEHLVLGH-UHFFFAOYSA-N DESCRIPTION General description An anti-hyperglycemic agent that acts by lowering the hepatic output of glucose. Does not stimulate insulin secretion, promote weight gain, or cause hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK), leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation. An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK) leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation. Biochem/physiol Actions Cell permeable: no Primary Target AMP-activated protein kinase (AMPK) Product does not compete with ATP. Reversible: no Packaging Packaged under inert gas Warning Toxicity: Irritant (B) Reconstitution Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Other Notes Cleasby, M.E., et al. 2004. Diabetes53, 3258. Klein, J., et al. 2004. J. Endocrinol.183, 299. Zhou, G., et al. 2001. J. Clin. Invest.108, 1167. Lin, H.Z., et al. 2000. Nat. Med.6, 998. Legal Information CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
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