Sigma-Aldrich E7750 N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride commercial grade, powder CAS No.: 25952-53-8 25 gr
Brand
Stock Code
LB.SA.E7750-25G
Kısa Bilgi
Synonym(s): N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC, EDC hydrochloride, WSC hydrochloride Empirical Formula (Hill Notation): C8H17N3 · HCl CAS Number: 25952-53-8 Molecular Weight: 191.70 Beilstein: 5764110 EC Number: 247-361-2 MDL number: MFCD00012503 PubChem Substance ID: 24894654 NACRES: NA.31
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Sigma-Aldrich E7750 N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
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Synonym(s): N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC, EDC hydrochloride, WSC hydrochloride
Empirical Formula (Hill Notation): C8H17N3 · HCl
CAS Number: 25952-53-8
Molecular Weight: 191.70
Beilstein: 5764110
EC Number: 247-361-2
MDL number: MFCD00012503
PubChem Substance ID: 24894654
NACRES: NA.31
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PROPERTIES
grade commercial grade
Quality Level 300
form powder
mp 110-115 °C (lit.)
solubility H2O: ≤100 mg/mL
storage temp. −20°C
SMILES string Cl.CCN=C=NCCCN(C)C
InChI 1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H
InChI key FPQQSJJWHUJYPU-UHFFFAOYSA-N
DESCRIPTION
Application
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride has been used for the formation of FND (fluorescent nanodiamonds)-transferrin bioconjugates.[1]
It has been used for crosslinking polyethylenimine to gold particles.[2]
It has been used as a carbodiimide linkage agent for coating of carboxylated polystyrene beads with biotinylated BSA (bovine serum albumin).[3]
Packaging
100 mg in poly bottle
1, 5, 10, 25, 100 g in poly bottle
1, 2.1, 5 kg in poly drum
Biochem/physiol Actions
Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.
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