Sigma-Aldrich G4796 Genipin ≥98% (HPLC), powder 25 mg
Brand
Stock Code
LB.SA.G4796-25MG
| Sigma-Aldrich G4796 Genipin ≥98% (HPLC), powder 25 mg |
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Synonym(s): Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate
Empirical Formula (Hill Notation): C11H14O5
CAS Number: 6902-77-8
Molecular Weight: 226.23
MDL number: MFCD00888600
PubChem Substance ID: 329799931
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PROPERTIES
Quality Level 100
assay ≥98% (HPLC)
form powder
solubility DMSO: ≥25 mg/mL, H2O: insoluble
SMILES string COC(=O)C1=CO[C@@H](O)C2C1CC=C2CO
InChI 1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
InChI key AZKVWQKMDGGDSV-BCMRRPTOSA-N
DESCRIPTION
General description
Genipin is a natural cross linking agent, which is extracted from gardenia fruit. It prevents lipid peroxidation and production of nitric oxide. Genipin protects the hippocampal neurons from the toxicity of Alzheimer′s amyloid β protein. It has anti-inflammatory and anti-angiogenesis effects. Genipin is involved in drug delivery system.
Application
Genipin has been used:
in chemosensitivity assay
in the preparation of recombinant human (rh)-odontogenic ameloblast-associated protein (ODAM) -impregnated collagen gel and in vitro mineralization assay
in genipin gel preparation
Packaging
25, 125 mg in glass bottle
Biochem/physiol Actions
Genipin stimulates insulin secretion in UCP2-dependent manner (Uncoupling protein 2). Genipin is a protein, collagen, gelatin, and chitosan cross-linker. |