Sigma Aldrich N4126 Nicotinic acid ≥98% 100 gr
Category
Brand
Stock Code
LB.SA.N4126-100G
Kısa Bilgi
Synonym(s): 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3 Empirical Formula (Hill Notation): C6H5NO2 CAS Number: 59-67-6 Molecular Weight: 123.11 Beilstein: 109591 EC Number: 200-441-0 MDL number: MFCD00006391 PubChem Substance ID: 24897668 NACRES: NA.25
| Sigma Aldrich N4126 Nicotinic acid ≥98% 100 gr |
|
Synonym(s): 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3
Empirical Formula (Hill Notation): C6H5NO2
CAS Number: 59-67-6
Molecular Weight: 123.11
Beilstein: 109591
EC Number: 200-441-0
MDL number: MFCD00006391
PubChem Substance ID: 24897668
NACRES: NA.25 |
|
PROPERTIES
biological source synthetic (organic)
Quality Level 200
Assay ≥98%
form powder
color white to off-white
mp 236-239 °C (lit.)
SMILES string OC(=O)c1cccnc1
InChI 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI key PVNIIMVLHYAWGP-UHFFFAOYSA-N
Gene Information human ... CYP1A2(1544) rat ... Chrnb2(54239)
DESCRIPTION
General description
Nicotinic acid is also known as vitamin B3 or Niacin. It is a water soluble vitamin. Niacin can be either synthesized within the body or can be obtained from dietary sources.[1]
Application
Nicotinic acid has been used:
as a component of the MS vitamins stock solution[2]
for the detection of siderophores in Escherichia coli bacterial culture[3]
as a component of the holidic medium for adult Drosophila [4].
Biochem/physiol Actions
Niacin is involved in the production of nicotinamide adenine dinucleotide (NAD+), which is used in the adenine triphosphate (ATP) production in mitochondrial oxidative phosphorylation.[1] It also decreases hepatic production of very-low density lipoproteins (VLDL), and apolipoprotein B (apo-B).[5] Niacin deficiency leads to pellagra.[6] |
