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Sigma-Aldrich N6252 Norharmane ≥98% (TLC), crystalline, monoamine oxidase inhibitor CAS No.: 244-63-3 1 gr
Brand
Stock Code
LB.SA.N6252-1G
Kısa Bilgi
Synonym(s): β-Carboline, 9H-Pyrido[3,4-b]indole Empirical Formula (Hill Notation): C11H8N2 CAS Number: 244-63-3 Molecular Weight: 168.19 NACRES: NA.77 PubChem Substance ID: 24897776 UNSPSC Code: 12352200 EC Number: 205-959-0 MDL number: MFCD00004956 Form: crystalline
| Sigma-Aldrich N6252 Norharmane ≥98% (TLC), crystalline, monoamine oxidase inhibitor |
| Sigma-Aldrich N6252 Norharmane ≥98% (TLC), crystalline, monoamine oxidase inhibitor CAS No.: 244-63-3 1 gr Synonym(s): β-Carboline, 9H-Pyrido[3,4-b]indole Empirical Formula (Hill Notation): C11H8N2 CAS Number: 244-63-3 Molecular Weight: 168.19 NACRES: NA.77 PubChem Substance ID: 24897776 UNSPSC Code: 12352200 EC Number: 205-959-0 MDL number: MFCD00004956 Form: crystalline |
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PROPERTIES
Product Name Norharmane, crystalline
form crystalline Quality Segment 200 color light yellow storage temp. 2-8°C SMILES string c1ccc2c(c1)[nH]c3cnccc23 InChI 1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H InChI key AIFRHYZBTHREPW-UHFFFAOYSA-N Gene Information human... IKBKB(3551) rat... Gabra2(29706) DESCRIPTION General description Norharmane is an alkaloid widely present in living organisms and can also be chemically synthesized. It is a β-carboline derivative composed of indole and pyridine. Application Norharmane has been used: - as a β-carboline to study its effect on nigrostriatal dopamine (DA) neurons - as an internal standard in gas chromatography-mass spectrometry (GC-MS) analyses using Conidiobulus coronatus filtrates - as a β-carboline-3-carboxylic acid N-methylamide (CMA) analog to study its binding ability with Mcm2-7 (minichromosome maintenance) Biochem/physiol Actions Inhibitor of indoleamine 2,3-dioxygenase (IDO). Norharmane and its derivative exhibit anti-cancer properties. It acts as a monoamine oxidase (MAO) inhibitor and might benefit Parkinson′s disease (PD). High levels of β-carboline in plasma are found in PD. |
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