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Sigma-Aldrich P2297 Picrylsulfonic acid solution 5 % (w/v) in H2O, BioReagent, suitable for determination of primary amines CAS No.: 2508-19-2 10 mL
Brand
Stock Code
LB.SA.P2297-10ML
Kısa Bilgi
Synonym(s): 2,4,6-Trinitrobenzenesulfonic acid solution, TNBS Empirical Formula (Hill Notation): C6H3N3O9S CAS Number: 2508-19-2 Molecular Weight: 293.17 Beilstein: 572358 MDL number: MFCD00064382 UNSPSC Code: 12352005 PubChem Substance ID: 24898307 NACRES: NA.25
| Sigma-Aldrich P2297 Picrylsulfonic acid solution 5 % (w/v) in H2O, BioReagent, suitable for determination of primary amines CAS No.: 2508-19-2 |
| Synonym(s): 2,4,6-Trinitrobenzenesulfonic acid solution, TNBS Empirical Formula (Hill Notation): C6H3N3O9S CAS Number: 2508-19-2 Molecular Weight: 293.17 Beilstein: 572358 MDL number: MFCD00064382 UNSPSC Code: 12352005 PubChem Substance ID: 24898307 NACRES: NA.25 |
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PROPERTIES
product line BioReagent
Quality Level 200 concentration 5 % (w/v) in H2O suitability suitable for determination of primary amines storage temp. 2-8°C SMILES string OS(=O)(=O)c1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O InChI 1S/C6H3N3O9S/c10-7(11)3-1-4(8(12)13)6(19(16,17)18)5(2-3)9(14)15/h1-2H,(H,16,17,18) InChI key NHJVRSWLHSJWIN-UHFFFAOYSA-N DESCRIPTION General description Picrylsulfonic acid solution is a hapten, which can bind to tissue proteins and turn into an antigen. This leads to several immunologic responses. Colitis induced by a 2,4,6-trinitrobenzene sulfonic acid (TNBS) is a type of delayed hypersensitivity reaction to haptenized proteins. Leukotriene B4 (LTB4) and the monhydroxyl fatty acids 5-hydroxyeicosatetraenoic acid (5-HETE), 12-HETE, and 15-HETE are the major inflammatory mediators involved in this TNBS-induced colitis. Ethanol when used in high concentration act as a vehicle for the TNBS administration. Application Hydrophilic modifying reagent. Derivatives with amino compounds can be regenerated with hydrazine. Picrylsulfonic acid solution has been used: - to assess the efficiency of carboxymethyl lysine (CML) modifications of exposed primary amines - to incubate zona intact bovine embryos for the differential staining of blastocysts - to induce irritable bowel syndrome (IBS) in mice and to study its effects on Clostridium butyricum |