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Sigma-Aldrich P1754 TWEEN® 80 viscous liquid CAS No.: 9005-65-6 500 mL

Stock Code
LB.SA.P1754-500ML
Kısa Bilgi
Synonym(s): TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80 CAS Number: 9005-65-6 MDL number: MFCD00082107 UNSPSC Code: 12161900 NACRES: NA.21
Stok Sorunuz
Sigma-Aldrich P1754 TWEEN® 80 viscous liquid CAS No.: 9005-65-6 
Synonym(s): TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80
CAS Number:
9005-65-6
MDL number:
MFCD00082107
UNSPSC Code:
12161900 N
ACRES:
NA.21
Sigma-Aldrich P1754 TWEEN® 80 viscous liquid CAS No.: 9005-65-6
PROPERTIES
biological source
Porcine (tallow)
bovine (tallow)
Quality Level
200
description
non-ionic
form
viscous liquid
mol wt
micellar avg mol wt 79,000
average mol wt 1310
composition
Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)
aggregation number
60 CMC 0.012 mM (20-25°C)
viscosity
400-620 mPa.s
transition temp
cloud point 65 °C
solubility
water: soluble, clear to slightly hazy, colorless to yellow
density
1.064 g/cm3 HLB 15
application(s) cell analysis
SMILES string
CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
InChI 1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
InChI key
RGPBUVUVZKQNHD-MDZDMXLPSA-N


DESCRIPTION

General description
Tween® 80 is a non-ionic detergent and surfactant, classified as an ester of sorbitan and oleic acid. It is a versatile compound commonly employed in various biological applications, including cell lysis, nuclei isolation, and cell fractionation. Additionally, Tween 80 finds use in stabilizing proteins and facilitating protein membrane studies. Its effectiveness stems from its membership in the polysorbate group, characterized by the combination of sorbitol and sorbitane oleic esters with polyethylene glycol chains. These structural features contribute to Tween 80′s emulsifying capabilities and a broad range of applications.
Application
Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines. TWEEN® 80 has been used in drug vehicle solution for specific injections in mice and rats.[1][2] It has been used for the determination of esterase activity in bacterial cells.[3]
Biochem/physiol Actions
TWEEN® 80 is a polysorbate surfactant which helps in stabilizing proteins and in protein membrane studies. It is regularly used for the extraction of membrane proteins and isolation of nuclei from cells.[4][5][6]
Features and Benefits
Excellent wetting and dispersing agent Highly versatile surfactant for your Cell Biology and Biochemical research
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Legal Information
TWEEN is a registered trademark of Croda International PLC
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Sigma-Aldrich P1754 TWEEN® 80 viscous liquid CAS No.: 9005-65-6 500 mL Synonym(s): TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80 CAS Number: 9005-65-6 MDL number: MFCD00082107 UNSPSC Code: 12161900 NACRES: NA.21 LB.SA.P1754-500ML
Sigma-Aldrich P1754 TWEEN® 80 viscous liquid CAS No.: 9005-65-6 500 mL

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