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Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem
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Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem

Kategori
Moleküler Biyoloji ve Biyokimya Ürünleri
Marka
SIGMA-ALDRICH
Stok Kodu
LB.SA.113000
Kısa Bilgi
Synonym(s): (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp Empirical Formula (Hill Notation): C5H9NO3 CAS Number: 51-35-4 Molecular Weight: 131.13 Beilstein: 81441 EC Number: 200-091-9 MDL number: MFCD00064320 PubChem Substance ID: 24895692 NACRES: NA.22
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Ürün Detayları
 Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem
CAS # Empirical Formula
65-61-2 C₁₇H₂₀ClN₃
  Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem
Description
Overview A cell-permeable, cationic fluorescent dye that interacts with DNA and RNA by intercalation or electrostatic attractions. When bound to DNA, it is spectrally very similar to fluorescein, with an excitation maximum at 502 nm and an emission maximum at 525 nm. Upon association with RNA, the excitation maximum shifts to 460 nm and the emission maximum shifts to 650 nm (red). Often used to measure single- and double-stranded DNA and RNA in the diagnosis, classification, and prognosis of many neoplasms. A very versatile fluorescent stain used in histochemistry and cytochemistry that can be used to provide information about the in situ content, molecular structure, and conformation of many nucleic acid-containing cell constituents.
Catalogue Number 113000
Brand Family Calbiochem®
Synonyms AO, 3,6-bis(Dimethylamino)acridine, HCl
References
References Gonzalez, K., et al. 1995. Curr. Eye Res. 14, 269.
Muro-Cacho, C.A., et al. 1995. J. Immunol. 154, 5555.
Olivier, R. 1995. Methods Enzymol. 251, 270.
Busch, G.L., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 9165.
Darzynkiewicz, Z. 1994. Methods Cell. Biol. 41, 401.
Delic, J., et al. 1991. Exp. Cell Res. 194, 147.
El-Naggar, A.K., et al. 1991. Cytometry 12, 330.
Lopez, F., et al. 1991. Cytometry 12, 42.
Gurrieri, S., et al. 1990. Biochemistry 29, 3396.
Hermansen, D.K., et al. 1989. Cytometry 10, 739.
Product Information
CAS number 65-61-2
ATP Competitive N
Form Burnt-orange solid
Hill Formula C₁₇H₂₀ClN₃
Chemical formula C₁₇H₂₀ClN₃
Hygroscopic Hygroscopic
Reversible N
Quality Level MQ100
Biological Information
Primary Target Interacts with DNA and RNA
Purity ≥98% by HPLC
Physicochemical Information
Cell permeable Y
Safety Information according to GHS
RTECS AR7601000
Safety Information
R Phrase R: 20/21/22-40

Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect.
S Phrase S: 36

Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +15°C to +30°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special Instructions Following reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 1 month at 4°C.
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Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem, Sigma-Aldrich 113000 Acridine Orange
Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem, Sigma-Aldrich 113000 Acridine Orange LB.SA.113000
Sigma-Aldrich 113000 Acridine Orange - CAS 65-61-2 - Calbiochem

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