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Sigma-Aldrich 42867 Dextran sulfate sodium salt Mr ~40,000 |
Synonym(s): DSS Dextran Sulfate Sodium UNSPSC Code: 12352201 NACRES: NA.25 |
PROPERTIES
form powder
Quality Level 100 mol wt Mr ~40,000 loss ≤10% loss on drying color white to off-white useful pH range 6.0-8 (10 g/L) mp (Decomposes on heating.) solubility water: soluble storage temp. room temp DESCRIPTION General description Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran. Application Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes. Biochem/physiol Actions Treatment with dextran sulfate sodium triggers development of colitis in mice and rats by binding to medium-chain-length fatty acids present in the colon and inducing inflammation. [1] Other Notes To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page. |