Sigma-Aldrich A5486 Azoxymethane 13.4 M, ≥98% CAS No.: 25843-45-2 100 mg
Marka
Stok Kodu
LB.SA.A5486-100MG
Kısa Bilgi
Synonym(s): AOM Linear Formula: CH3N=N(→O)CH3 CAS Number: 25843-45-2 Molecular Weight: 74.08 MDL number: MFCD00126912 UNSPSC Code: 12352124 PubChem Substance ID: 329770827 NACRES: NA.25
| Sigma-Aldrich A5486 Azoxymethane 13.4 M, ≥98% CAS No.: 25843-45-2 |
| Synonym(s): AOM Linear Formula: CH3N=N(→O)CH3 CAS Number: 25843-45-2 Molecular Weight: 74.08 MDL number: MFCD00126912 UNSPSC Code: 12352124 PubChem Substance ID: 329770827 NACRES: NA.25 |
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PROPERTIES
Quality Level 200
Assay ≥98% form liquid composition methylene chloride, ≤1% storage condition (Keep container tightly closed in a dry and well-ventilated place.) concentration 13.4 M color colorless bp 97-99 °C (lit.) density 0.991 g/mL at 25 °C (lit.) application(s) genomic analysis storage temp. −20°C SMILES string C\N=[N+](/C)[O-] InChI 1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+ InChI key DGAKHGXRMXWHBX-ONEGZZNKSA-N DESCRIPTION General description Azoxymethane (AOM) is a potent laboratory chemical used to study cancer initiation, progression, and prevention, particularly in the colon. It acts as both a carcinogen, triggering tumor formation, and a gene mutation agent, causing specific alterations in DNA. Application Azoxymethane (AOM), a gene mutation agent, may be used with dextran sulfate sodium (DSS) to create cancer models in laboratory animals which can be used to study mechanisms of cancer progression and chemoprevention. Biochem/physiol Actions Carcinogen that induces O6-methylguanine adducts in DNA leading to G→A transitions. Induces tumorigenesis in the colon of laboratory animals and is used to study the mechanism of cancer progression and chemoprevention. Features and Benefits Versatile and adaptable for a wide variety of laboratory and research applications. Other Notes For additional information on our range of Biochemicals, please complete this form. It is critical to determine the correct dosage of Azoxymethane for the experimental design to avoid premature death of laboratory animals. |
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