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Sigma-Aldrich B81255 N-Bromosuccinimide 99%, for peptide synthesis, ReagentPlus® CAS No.: 128-08-5 500 gr
Marka
Stok Kodu
LB.SA.B81255-500G
Kısa Bilgi
Synonym(s): NBS Empirical Formula (Hill Notation): C4H4BrNO2 CAS Number: 128-08-5 Molecular Weight: 177.98 Beilstein: 113916 EC Number: 204-877-2 MDL number: MFCD00005510 UNSPSC Code: 12352101 PubChem Substance ID: 57653959 NACRES: NA.22
Sigma-Aldrich B81255 N-Bromosuccinimide 99%, for peptide synthesis, ReagentPlus® |
Synonym(s): NBS Empirical Formula (Hill Notation): C4H4BrNO2 CAS Number: 128-08-5 Molecular Weight: 177.98 Beilstein: 113916 EC Number: 204-877-2 MDL number: MFCD00005510 UNSPSC Code: 12352101 PubChem Substance ID: 57653959 NACRES: NA.22 |

PROPERTIES
Product Name N-Bromosuccinimide, ReagentPlus®, 99%
Quality Level 200 product line ReagentPlus® Assay 99% form powder mp 175-180 °C (dec.) (lit.) application(s) peptide synthesis storage temp. 2-8°C SMILES string BrN1C(=O)CCC1=O InChI 1S/C4H4BrNO2/c5-6-3(7)1-2-4(6)8/h1-2H2 InChI key PCLIMKBDDGJMGD-UHFFFAOYSA-N DESCRIPTION General description N-Bromosuccinimide (NBS) is an organic compound commonly used as a brominating agent in organic synthesis. It is a convenient source of bromine radicals. It is used in radical bromination of allylic and benzylic positions. Additionally, NBS is also used as a reagent in electrophilic addition and electrophilic substitution reactions in organic chemistry. Application N-Bromosuccinimide can be used as a reagent: - In the Wohl-Ziegler reaction (bromination at allylic positions via a radical pathway). - To synthesize benzils and aliphatic 1,2-diketones from hydrobenzoins and 1,2-diols in the presence of CCl4 as a solvent. - To prepare tricyclic azepino[4,5-b]indoles from indole-β-enaminoesters or β-enaminones via Pictet–Spengler cyclization. - To synthesize acylsilanes via oxidative hydrolysis of 2-silyl-1,3-dithianes. Versatile brominating agent. For the oxidation of tryptophan though tyrosine, histidine and methionine residues may be oxidized to a lesser extent. Also used for the modification of ribosomal sulfhydryl groups. Features and Benefits NBS is an easier and safer brominating agent to handle than bromine. Legal Information ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
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