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Sigma-Aldrich C1879 Choline chloride ≥98% CAS No: 67-48-1 500 gr
Marka
Stok Kodu
LB.SA.C1879-500G
Kısa Bilgi
Synonym(s): (2-Hydroxyethyl)trimethylammonium chloride Linear Formula: (CH3)3N(Cl)CH2CH2OH CAS Number: 67-48-1 Molecular Weight: 139.62 Beilstein: 3563126 EC Number: 200-655-4 MDL number: MFCD00011721 PubChem Substance ID: 57653990 NACRES: NA.77
| Sigma-Aldrich C1879 Choline chloride ≥98% 500 gr |
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Synonym(s): (2-Hydroxyethyl)trimethylammonium chloride
Linear Formula: (CH3)3N(Cl)CH2CH2OH
CAS Number: 67-48-1
Molecular Weight: 139.62
Beilstein: 3563126
EC Number: 200-655-4
MDL number: MFCD00011721
PubChem Substance ID: 57653990
NACRES: NA.77
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PROPERTIES
biological source synthetic
Quality Level 200
assay ≥98%
form powder or crystals
technique(s) cell culture | mammalian: suitable
color colorless to white
mp 302-305 °C (dec.) (lit.)
SMILES string [Cl-].C[N+](C)(C)CCO
InChI 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key SGMZJAMFUVOLNK-UHFFFAOYSA-M
DESCRIPTION
General description
Choline chloride is the synthetic form of vitamin B4, choline and is a common poultry feed.[1]
Application
Choline chloride has been used:
as a substrate for measuring choline oxidase enzyme activity using fluorescence measurements[2]
as a component of non-physiological buffers for testing calcium based inhibition of cytochrome c oxidaseP[3]
as a component of perfusate solution for studying arterial pressure in jejunum samples[4]
Packaging
500 g in poly bottle 1, 5 kg in poly drum
Biochem/physiol Actions
Choline chloride treatment of radish seeds modulates phosphatidylcholine and phosphatidylethanolamine levels.[5] It elicits hepatoprotective effects and modulates methyl carbon based metabolic pathways.[6] The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes.
Substrates
Choline acetyltransferase substrate
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