Sigma-Aldrich SRP4304 NGF-beta from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE) 20 μG
Marka
Stok Kodu
LB.SA.SRP4304-20UG
Kısa Bilgi
Synonym(s): Nerve Growth Factor β, Ngf, Ngfb NACRES: NA.32
| Sigma-Aldrich SRP4304 NGF-beta from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE) 20 μG |
|
Synonym(s): Nerve Growth Factor β, Ngf, Ngfb
NACRES: NA.32
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PROPERTIES
biological source mouse
recombinant expressed in E. coli
assay ≥98% (SDS-PAGE)
form lyophilized
potency 0.2 ng/mL ED50
mol wt ~13.4 kDa
packaging pkg of 20 μg
impurities endotoxin, tested
NCBI accession no. P01139
shipped in wet ice
storage temp. −20°C
Gene Information mouse ... Ngf(18049)
DESCRIPTION
General description
Nerve growth factor-β (NGF-β) belongs to the neurotrophin family.[1] The active form of human NGF-β is a homodimer, non-glycosylated chain.[2]
Packaging
20 μg
Biochem/physiol Actions
Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells.[1] It brings pro-survival effects with the help of receptor tyrosine kinase TrkA.[3] NGF-β is associated with diabetic neuropathy and ischemic heart disease.[1] It is also involved in airway nerve system.[4] NGF-β is also responsible for the pain which is linked with osteoarthritis (OA).[5] It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.[6]
Physical form
Lyophilized without any additives.
Reconstitution
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles. Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use. |
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