Merck 101791 L-Glutamic acid EMPROVE® EXPERT Ph Eur, JP 10 kg

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MERCK

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LB.M.1017919010

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Merck 101791 L-Glutamic acid EMPROVE® EXPERT Ph Eur, JP 10 kg
Catalogue Number	101791
Synonyms	L-a-Aminoglutaric acid, Glu, L-alpha-Aminoglutaric acid, L-α-Aminoglutaric acid

Merck 101791 L-Glutamic acid EMPROVE® EXPERT Ph Eur, JP

Product Information
CAS number	56-86-0
EC number	200-293-7
Grade	Ph Eur,JP
Hill Formula	C₅H₉NO₄
Molar Mass	147.13 g/mol
HS Code	2922 42 00
Structure formula Image
Quality Level	MQ500

Physicochemical Information
Density	1.54 g/cm3 (20 °C)
Melting Point	160 °C
pH value	3.0 - 3.5 (8.6 g/l, H₂O, 25 °C)
Vapor pressure	<0.1 hPa (20 °C)
Bulk density	460 kg/m3
Solubility	11.1 g/l

Toxicological Information
LD 50 oral	LD50 Rat > 30000 mg/kg

Safety Information according to GHS
RTECS	LZ9700000
Storage class	10 - 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

Storage and Shipping Information
Storage	Store at +5 °C to +30 °C.

Transport Information
Declaration (railroad and road) ADR, RID	Kein Gefahrgut
Declaration (transport by air) IATA-DGR	No Dangerous Good
Declaration (transport by sea) IMDG-Code	No Dangerous Good

Specifications
Assay (alkalimetric, calculated on dried substance)	99.0 - 100.5 %
Identity (IR-spectrum)	passes test
Identity (specific rotation)	passes test
Appearance	white to almost white, crystalline powder or colorless crystals
Appearance of solution (100 g/l, hydrochloric acid 1 mol/l)	clear and colorless
Appearance of solution (100 g/l, hydrochloric acid 2 mol/l)	clear and colorless
Spec. rotation (α 20/D, 100 g/l, hydrochloric acid 1 mol/l, calc. on dried substance)	+30.5 to +32.5
Spec. rotation (α 20/D, 100 g/l, hydrochloric acid 2 mol/l, calc. on dried substance)	+31.5 to +32.5
pH (7 g/l CO₂-free water)	2.9 - 3.9
Chloride (Cl)	≤ 200 ppm
Sulfate (SO₄)	≤ 200 ppm
Heavy metals (as Pb)	≤ 10 ppm
Fe (Iron)	≤ 10 ppm
NH₄ (Ammonium)	≤ 200 ppm
Ninhydrin - positive substances (TLC)	≤ 0.5 %
Related substances (LC) (largest single impurity)	≤ 0.2 %
Related substances (LC) (Sum of all impurities)	≤ 0.6 %
Residual solvents (ICH (Q3C))	excluded by manufacturing process
Sulfated ash (600 °C)	≤ 0.1 %
Loss on drying (105 °C; 3 h)	≤ 0.3 %
Bacterial endotoxins	≤ 25 I.U./g
Total aerobic microbial count (TAMC)	≤ 100 CFU/g
Total combined yeasts/moulds count (TYMC)	≤ 100 CFU/g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., JP

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Merck 101791 L-Glutamic acid EMPROVE® EXPERT Ph Eur, JP 10 kg

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